Instructions are presented to ensure the transport of Neisseria meningitidis in viable state from remote sites to a diagnostic laboratory. Precautions are outlined which are necessary to prevent the accidental release of pathogenic material during shipment. In addition, instructions are provided for the handling of initial isolate material (e.g. on swabs or in cerebrospinal fluid (CSF)). The described shipping procedures are in accordance with IATA Packing Notes for Passenger and Cargo...
Topics: DTIC Archive, Spence,M R, DEFENCE RESEARCH ESTABLISHMENT SUFFIELD RALSTON (ALBERTA), *PATHOGENIC...
This slide presentation reviews the effects of enhanced exposure to CO2 on Earth and in space. The effects of enhanced exposure to CO2 are experienced in almost all bodily systems. In space some of the effects are heightened due to the fluid shifts to the thorax and head. This fluid shift results in increased intracranial pressure, congested cerebral circulation, increased Cerebral Blood Flow (CBF) and Intravenous dilatation. The mechanism of the effect of CO2 on CBF is diagrammed, as is the...
Topics: NASA Technical Reports Server (NTRS), BRAIN CIRCULATION, CARBON DIOXIDE, FLUID SHIFTS (BIOLOGY),...
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898
Feb 20, 2009
02/09
by
American Physiological Society (1887- )
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Book digitized by Google and uploaded to the Internet Archive by user tpb.
Topics: blood, dbygoogic, experiments, pressure, normal, gastric, fluid, injection, stimulation, thyroid,...
Source: http://books.google.com/books?id=TZ8EAAAAYAAJ&oe=UTF-8
Using dogs, it was found that d-amphetamine (3 mg/kg i.v.) produces a threefold increase in CSF levels of the norepinephrine metabolite MHPG. L-amphetamine at the same dosage level produced either no change in MHPG or had a relatively smaller effect. Cerebral blood flow increased threefold with d-amphetamine at 3 mg/kg in dogs, and only slightly after the 1-isomer at the same dose. Arterial pressure doubled after d-amphetamine (3 mg/kg) and only increased 20-30% after the 1-isomer at the same...
Topics: DTIC Archive, Burns,Barry, JOHNS HOPKINS UNIV BALTIMORE MD DEPT OF ENVIRONMENTAL MEDICINE, *DRUG...
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54
Sep 26, 2014
09/14
by
Surgucheva, Irina; Newell, Kathy L; Burns, Jeffrey; Surguchov, Andrei
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This article is from Acta Neuropathologica Communications , volume 2 . Abstract Introduction: Several neurodegenerative diseases are classified as proteopathies as they are associated with the aggregation of misfolded proteins. Synucleinopathies are a group of neurodegenerative disorders associated with abnormal deposition of synucleins. α-Synucleinopathies include Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy. Recently accumulation of another member of the...
Topics: astrocytes, antibodies, antibody, lewy, substantia, brain, amygdala, surgucheva, nigra, dlb,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172890
INTRODUCTION: Current long-duration missions to the International Space Station and future exploration-class missions beyond low-Earth orbit, such as to Mars and asteroids, expose astronauts to increased risk of Visual Impairment and Intracranial Pressure (VIIP) syndrome [1]. It has been hypothesized that the headward shift of cerebral spinal fluid (CSF) and blood in microgravity may cause significant elevation of intracranial pressure (ICP), which in turn induces VIIP syndrome through...
Topics: NASA Technical Reports Server (NTRS), CENTRAL NERVOUS SYSTEM, LUMPED PARAMETER SYSTEMS, SPACE...
Rifampin was administered orally in one dose of 25 mg per kg of body weight to 6 patients with tuberculous meningitis who had received no previous antituberculous chemotherapy and to 7 control subjects. There was no sigificant difference in rifampin absorption at 3 hours between patients and control subjects; however, no rifampin could be detected in the 3-hour cerebrospinal fluid (CSF) specimens taken from control subjects. Significant concentrations were reached in patients' CSF within 3...
Topics: DTIC Archive, Sippel, John E., Mikhail, Isis A., Girgis, Nabil I., Youssef, Hassan H., NAVAL...
Long-duration space flight carries the risk of developing Visual Impairment and Intracranial Pressure (VIIP) syndrome, a spectrum of ophthalmic changes including posterior globe flattening, choroidal folds, distension of the optic nerve sheath (ONS), optic nerve kinking and potentially permanent degradation of visual function. The slow onset of VIIP, its chronic nature, and certain clinical features strongly suggest that biomechanical factors acting on the ONS play a role in VIIP. Here we...
Topics: NASA Technical Reports Server (NTRS), OPHTHALMOLOGY, EYE (ANATOMY), INTRACRANIAL PRESSURE,...
Preliminary results are based on analyses of data from 17 crewmembers. The initial analysis compares pre to post-flight changes in total cerebral blood flow (CBF) and craniospinal CSF flow volume. Total CBF is obtained by summation of the mean flow rates through the 4 blood vessels supplying the brain (right and left internal carotid and vertebral arteries). Volumetric flow rates were obtained using an automated lumen segmentation technique shown to have 3-4-fold improved reproducibility and...
Topics: NASA Technical Reports Server (NTRS), MAGNETIC RESONANCE, IMAGING TECHNIQUES, CEREBROSPINAL FLUID,...
The present study was designed to investigate whether alterations, within physiological ranges, in the concentrations of various CSF cations (e.g., Na+, K+, Ca2+, Mg2+) could affect the basal activity of the HHA system directly or through their actions on neurotransmitters which are known to modulate the activity of the hypophysiotropic area. Adult male and female cats were prepared with left lateral cerebroventricular and right atrial cannulae. These studies demonstrated that although elevated...
Topics: DTIC Archive, Marotta,S F, ILLINOIS UNIV AT THE MEDICAL CENTER CHICAGO RESEARCH RESOURCES CENTER,...
Current long-duration missions to the International Space Station and future exploration-class missions beyond low-Earth orbit expose astronauts to increased risk of Visual Impairment and Intracranial Pressure (VIIP) syndrome. It has been hypothesized that the headward shift of cerebrospinal fluid (CSF) and blood in microgravity may cause significant elevation of intracranial pressure (ICP), which in turn may then induce VIIP syndrome through interaction with various biomechanical pathways....
Topics: NASA Technical Reports Server (NTRS), AEROSPACE MEDICINE, CENTRAL NERVOUS SYSTEM, INTRACRANIAL...
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146
Apr 16, 2010
04/10
by
cohenjoshua@rocketmail.com
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BACKGROUND ... Marco's story is about a gay Quebecois and mentally challenged (and/or or mentally special/exotic as he preferred to call himself) trying to find acceptance. Instead, Marco found rejection from those around him, except for the rare few who understood what he stood for; and simply they were principles of supporting small businesses, ecological responsibility (i.e., reuse, reduce and recycle), promoting French culture and its language, as well as human rights and dignity,...
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Topics: headaches, migraines, spinal headaches, abdominal pains, generalized body stiffness, medical...
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169
Apr 16, 2010
04/10
by
cohenjoshua@rocketmail.com
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BACKGROUND ... Marco's story is about a gay Quebecois and mentally challenged (and/or or mentally special/exotic as he preferred to call himself) trying to find acceptance. Instead, Marco found rejection from those around him, except for the rare few who understood what he stood for; and simply they were principles of supporting small businesses, ecological responsibility (i.e., reuse, reduce and recycle), promoting French culture and its language, as well as human rights and dignity,...
Topics: headaches, migraines, spinal headaches, abdominal pains, generalized body stiffness, medical...
Long duration spaceflight has been associated with detrimental alterations in human sensorimotor systems and neurocognitive performance. Prolonged exposure to a head-down tilt position during long duration bed rest can resemble several effects of the microgravity environment such as reduced sensory inputs, body unloading and increased cephalic fluid distribution. The question of whether microgravity affects other central nervous system functions such as brain functional connectivity and its...
Topics: NASA Technical Reports Server (NTRS), ENVIRONMENT EFFECTS, PHYSIOLOGICAL EFFECTS, LONG DURATION...
Most of the sound frequencies used in these recordings correspond either to the molar mass or equivalent scalar octave of the related products. This work is dedicated to the public domain and may be reproduced without authorization. http://resonant-therapy.webs.com Algorithmic piano music mixed with sound frequencies. Public Domain * Allergic Rhinitis, also known as hay fever, is related to keratoconjunctivitis and atopy, and has symptoms including history of seasonal allergies, conjunctival...
Topics: Genetic Superpathways-Bone Deterioration, Genetic Superpathways-Bone Remodeling, Genetic...